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Chemical Structure : MM-102
CAS No.: 1417329-24-8
Catalog No.: PC-42922Not For Human Use, Lab Use Only.
MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $228 | In stock | |
| 25 mg | $388 | In stock | |
| 50 mg | $598 | In stock | |
| 100 mg | Get quote |
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MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM.
MM-102 effectively decreases the expression of HoxA9 and Meis-1.
MM-102 specifically inhibits cell growth and induces apoptosis in leukemia cells harboring MLL1 fusion proteins.
| M.Wt | 669.8049 | |
| Formula | C35H49F2N7O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Cyclopentanecarboxamide, 1-[[(2S)-5-[(aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]- |
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1. Karatas H, et al. J Am Chem Soc. 2013 Jan 16;135(2):669-82.
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