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Chemical Structure : MRT68921 hydrochloride
CAS No.: 2080306-21-2
Catalog No.: PC-42021Not For Human Use, Lab Use Only.
MRT-68921 hydrochloride (MRT68921) is a potent, relatively specific inhibitor of both ULK1 and ULK2 with IC50 of 2.9 and 1.1 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | Get quote |
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MRT68921 hydrochloride (MRT68921) is a potent, relatively specific inhibitor of both ULK1 and ULK2 with IC50 of 2.9 and 1.1 nM, respectively.
MRT-68921 hydrochloride inhibits a number of kinases by over 80% in a broad panel of 80 protein kinases, including TBK1 and AMPK.
MRT-68921 hydrochloride reduces phospho-ATG13 and blocks autophagy in cells.
| M.Wt | 471.038 | |
| Formula | C25H35ClN6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 10 mg/mL |
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| Chemical Name/SMILES |
Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-,hydrochloride (1:2) |
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1. Petherick KJ, et al. J Biol Chem. 2015 May 1;290(18):11376-83.
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