MS9117

Chemical Structure : MS9117

Catalog No.: PC-24632Not For Human Use, Lab Use Only.

MS9117 is a potent, selective CRBN-based LSD1 PROTAC degrader, effectively degrades LSD1 and demonstrates superior antiproliferative effects in AML cells.

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Biological Activity

MS9117 is a potent, selective CRBN-based LSD1 PROTAC degrader, effectively degrades LSD1 and demonstrates superior antiproliferative effects in AML cells.

Physicochemical Properties

M.Wt	938.95
Formula	C46H48F2N10O10
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(4-aminopiperidin-1-yl)-4-(4-cyano-3-fluorophenyl)-5-(3-fluoro-4-methoxyphenyl)-6-oxopyrimidin-1(6H)-yl)-N-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamido)ethoxy)ethoxy)ethyl)acetamide

References

1. Hosseini A, et al. roc Natl Acad Sci U S A. 2025 May 20;122(20):e2425812122.

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MS9117

Biological Activity

Physicochemical Properties

References

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