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Methylnaltrexone bromide

Chemical Structure : Methylnaltrexone bromide

CAS No.: 73232-52-7

Methylnaltrexone bromide

Catalog No.: PC-45960Not For Human Use, Lab Use Only.

A peripherally-acting μ-opioid antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals..

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Biological Activity

A peripherally-acting μ-opioid antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals.

Other Indication

Approved

Physicochemical Properties

M.Wt 436.3394
Formula C21H26BrNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 31 mg/mL

Chemical Name/SMILES

Morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, bromide, (5α)-

References

1. Yuan CS, et al. Eur J Pharmacol. 1995 Mar 24;276(1-2):107-11.

2. Foss JF, et al. Life Sci. 1996;59(15):PL235-8.

3. Foss JF, et al. J Clin Pharmacol. 1993 Aug;33(8):747-51.

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