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Chemical Structure : NS3861
Catalog No.: PC-60819Not For Human Use, Lab Use Only.
A potent, subtype-selective α3β4 nAChR partial agonist with Ki of 0.62 nM.
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A potent, subtype-selective α3β4 nAChR partial agonist with Ki of 0.62 nM; selectively activates receptors containing β4- but not β2-subunits, shows no efficacy at α4β2 receptors and only marginal efficacy at α4β4 receptors expressed in oocytes; enhances fecal pellet expulsion in a dose-dependent manner in mice that received long-term, but not short-term, morphine treatment.
| M.Wt | 400.29 | |
| Formula | C12H14BrNS.C4H4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Harpsøe K, et al. J Biol Chem. 2013 Jan 25;288(4):2559-70.
2. Gade AR, et al. J Pharmacol Exp Ther. 2016 Jun;357(3):520-8.
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