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NSC-639829

Chemical Structure : NSC-639829

CAS No.: 134742-19-1

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NSC-639829 (NSC639829)

Catalog No.: PC-60870Not For Human Use, Lab Use Only.

NSC-639829 is a potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NSC-639829 is a potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization.

    Physicochemical Properties

    M.Wt 470.327
    Formula C21H20BrN5O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-(dimethylamino)benzamide

    References

    1. Abdel-Aziz W, et al. Invest New Drugs. 2003 Nov;21(4):421-8.

    2. Jain A, et al. AAPS PharmSciTech. 2003 Oct 15;4(4):E52.

    3. Balcer-Kubiczek EK, et al. Cancer Chemother Pharmacol. 2007 May;59(6):781-7.

    4. Hallur G, et al. J Med Chem. 2006 Apr 6;49(7):2357-60.

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