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Chemical Structure : PA-824
CAS No.: 187235-37-6
Catalog No.: PC-42714Not For Human Use, Lab Use Only.
Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $188 | In stock | |
| 100 mg | $358 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
Bulk size, bulk discount!
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Pretomanid (PA-824) is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid.
Pretomanid (PA-824) exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL).
Pretomanid (PA-824) shows potent bactericidal activity against MDR M. tuberculosis and promising oral activity in animal infection models.
| M.Wt | 359.2574 | |
| Formula | C14H12F3N3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 33 mg/mL |
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| Chemical Name/SMILES |
5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-, (6S)- |
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1. Stover CK, et al. Nature. 2000 Jun 22;405(6789):962-6.
2. Tyagi S, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2289-93.
3. Lenaerts AJ, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2294-301.
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