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PF-07799933

Chemical Structure : PF-07799933

CAS No.:

PF-07799933 (ARRY-440)

Catalog No.: PC-22523Not For Human Use, Lab Use Only.

PF-07799933 (ARRY-440) is a brain-penetrant, selective, pan-mutant BRAF inhibitor, disrupts endogenous mutant-BRAF:wild-type-CRAF dimers, and spare是wild-type ERK signaling.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PF-07799933 (ARRY-440) is a brain-penetrant, selective, pan-mutant BRAF inhibitor, disrupts endogenous mutant-BRAF:wild-type-CRAF dimers, and spares wild-type ERK signaling.

Physicochemical Properties

M.Wt
Formula
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

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