Chemical Structure : PF-07799933
Catalog No.: PC-22523Not For Human Use, Lab Use Only.
PF-07799933 (ARRY-440) is a brain-penetrant, selective, pan-mutant BRAF inhibitor, disrupts endogenous mutant-BRAF:wild-type-CRAF dimers, and spare是wild-type ERK signaling.
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PF-07799933 (ARRY-440) is a brain-penetrant, selective, pan-mutant BRAF inhibitor, disrupts endogenous mutant-BRAF:wild-type-CRAF dimers, and spares wild-type ERK signaling.
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Appearance | Solid | |
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Solubility |
10 mM in DMSO |
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