Catalog No.: PC-21295Not For Human Use, Lab Use Only.
PTC-124 (Ataluren, PTC124) is an orally bioavailable small molecule that selectively induces ribosomal readthrough of premature but not normal termination codons.
PTC-124 (Ataluren, PTC124) is an orally bioavailable small molecule that selectively induces ribosomal readthrough of premature but not normal termination codons. PTC-124 (Ataluren) promotes suppression of the human CFTR-G542X nonsense allele in cystic fibrosis (CF) mouse model. PTC-124 (Ataluren) is a potent firefly luciferase (FLuc) inhibitor with IC50 of 7 nM. PTC-124 (Ataluren) promotes ribosomal readthrough of premature stop codons in mRNA and offers therapeutic potential for multiple genetic diseases.
