Catalog No.: PC-62610Not For Human Use, Lab Use Only.
Pterostilbene is a natural phenolic compound, dimethylated derivative of resveratrol that has potent antitumor activity against several human cancer types.
Pterostilbene is a natural phenolic compound, dimethylated derivative of resveratrol that has potent antitumor activity against several human cancer types.
Pterostilbene induces strong and sustained activation of ERK1/2, with concomitant cyclin D1 suppression and p21 up-regulation, and inhibits the phosphorylation of AKT and mTOR in MDA-MB-468 cells.
Pterostilbene synergizes the antineoplastic effects of megestrol acetate in endometrial cancer.
Pterostilbene also targets MTA1/HDAC signaling with deacetylation of tumor suppressors p53 and PTEN in prostate cancer cells.
Physicochemical Properties
M.Wt
256.301
Formula
C16H16O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-Stilbenol, 3',5'-dimethoxy-, (E)- (8CI)
References
1. Chatterjee K, et al. Nutrients. 2018 Feb 21;10(2). pii: E243.
2. Butt NA, et al. Cancer Med. 2017 Nov;6(11):2673-2685.
3. Wakimoto R, et al. Anticancer Res. 2017 Nov;37(11):6153-6159.
