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Chemical Structure : Radotinib
CAS No.: 926037-48-1
Catalog No.: PC-38025Not For Human Use, Lab Use Only.
Radotinib (IY-5511) is a potent and selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM for wild-type BCR-ABL1 kinase..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $218 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | $698 | In stock | |
| 250 mg | Get quote |
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Radotinib (IY-5511) is a potent and selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM for wild-type BCR-ABL1 kinase.
| M.Wt | 530.5 | |
| Formula | C27H21F3N8O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzamide |
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1. Kim SH, et al. Haematologica. 2014 Jul;99(7):1191-6.
2. Heo SK, et al. PLoS One. 2015 Jun 12;10(6):e0129853.
3. Kwak JY, et al. Clin Cancer Res. 2017 Dec 1;23(23):7180-7188.
4. Heo SK, et al. Sci Rep. 2017 Nov 10;7(1):15278.
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