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Chemical Structure : SNAP 5114
Catalog No.: PC-61113Not For Human Use, Lab Use Only.
A GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively.
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A GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively; increases thalamic GABA levels and is an anticonvulsant following systemic administration in vivo.
| M.Wt | 505.61 | |
| Formula | C30H35NO6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dhar TG, et al. J Med Chem. 1994 Jul 22;37(15):2334-42.
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3. Doengi M, et al. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17570-5.
4. Dvorzhak A, et al. J Physiol. 2010 Jul 1;588(Pt 13):2351-60.
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