Chemical Structure : SNAP5114
CAS No.:
157604-55-2
SNAP5114
(SNAP-5114, (S)-SNAP 5114)
Catalog No. : PC-61113Not For Human Use, Lab Use Only.
SNAP5114 is a GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6111301
Biological Activity
SNAP5114 is a GABA transport inhibitor with IC50 of 5, 21, 388 and 140 uM for hGAT-3, rGAT-2, hGAT-1 and BGT-1, respectively.
Physicochemical Properties
M.Wt
505.61
Formula
C30H35NO6
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-(S)-3-piperidinecarboxylic acid
References
1. Dhar TG, et al. J Med Chem. 1994 Jul 22;37(15):2334-42.
2. Christiansen B, et al. J Biol Chem. 2007 Jul 6;282(27):19331-41.
3. Doengi M, et al. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17570-5.
4. Dvorzhak A, et al. J Physiol. 2010 Jul 1;588(Pt 13):2351-60.
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