Catalog No.: PC-35991Not For Human Use, Lab Use Only.
SRS11-92 (SRS 11-92) is a small molecule inhibitor of Ferroptosis and a derivative of Ferrostatin-1 (Fer-1), inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells with EC50 of 6 nM.
SRS11-92 (SRS 11-92) is a small molecule inhibitor of Ferroptosis and a derivative of Ferrostatin-1 (Fer-1), inhibits ferroptotic cell death induced by erastin in HT-1080 human fibrosarcoma cells with EC50 of 6 nM.
SRS11-92 inhibits iron-induced cell death in isolated mouse kidney proximal tubules at 2 uM.
SRS11-92 fully protects rat oligodendrocytes from cystine deprivation-induced cell death in an in vitro model of periventricular leukomalacia when used at a concentration of 100 nM.
SRS11-92 also increases survival of medium spiny neurons in rat corticostriatal brain slices in an in vitro model of Huntington’s disease in a concentration-dependent manner.
