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Chemical Structure : STX-213
Catalog No.: PC-61430Not For Human Use, Lab Use Only.
An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM.
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An orally active, second-generation steroid sulfatase inhibitor with IC50 of 0.5 nM; completely inhibits liver and tumor STS activity, and fully inhibits growth of MCF-7STS tumors in vivo.
| M.Wt | 420.524 | |
| Formula | C21H28N2O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Foster PA, et al. Clin Cancer Res. 2006 Sep 15;12(18):5543-9.
2. Foster PA, et al. Breast Cancer Res Treat. 2008 Sep;111(1):129-38.
3. Foster PA, et al. Endocrinology. 2008 Aug;149(8):4035-42.
4. Foster PA, et al. Clin Cancer Res. 2008 Oct 15;14(20):6469-77.
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