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Vinblastine

Chemical Structure : Vinblastine

CAS No.: 865-21-4

Vinblastine

Catalog No.: PC-45239Not For Human Use, Lab Use Only.

Vinblastine is a cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules, a chemotherapy agent for treatment of a number of types of cancer.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Vinblastine is a cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules, a chemotherapy agent for treatment of a number of types of cancer.

Physicochemical Properties

M.Wt 810.9741
Formula C46H58N4O9
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 42 mg/mL

Chemical Name/SMILES

Dimethyl(2β,3β,4β,5α,12β,19α)-15-[(5S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3,4-dicarboxylate

References

1. McKay DB, et al.  Proc Soc Exp Biol Med. 1993 Jul;203(3):372-6.
2. Bánóczi Z, et al. Bioconjug Chem. 2010 Nov 17;21(11):1948-55.

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