Chemical Structure : Yohimbine
CAS No.: 146-48-5
Catalog No.: PC-43161Not For Human Use, Lab Use Only.
Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C.
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Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C.
Yohimbine shows moderate affinity for the α1 receptor, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1F, 5-HT2B, and D2 receptors, and weak affinity for the 5-HT1E, 5-HT2A, 5-HT5A, 5-HT7, and D3 receptors.
M.Wt | 354.4427 | |
Formula | C21H26N2O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16α,17α)- |
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2. Arthur JM, et al. Biochem Pharmacol. 1993 Jun 9;45(11):2337-41.
3. Pérez Piñero C, et al. Br J Pharmacol. 2012 May;166(2):721-36.
4. Baxter GS, et al. Br J Pharmacol. 1994 May;112(1):323-31.
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