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Chemical Structure : ZD-7288
CAS No.: 133059-99-1
Catalog No.: PC-70127Not For Human Use, Lab Use Only.
ZD-7288 (ICI-D 7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.
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|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $228 | In stock | |
| 25 mg | $368 | In stock | |
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ZD-7288 (ICI-D 7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.
ZD-7288 inhibits the hyperpolarization activated cationic current (If) in a concentration-dependent manner in rat brain.
| M.Wt | 292.81 | |
| Formula | C15H21ClN4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(Z)-N-ethyl-1,2-dimethyl-6-(methylimino)-N-phenyl-1,6-dihydropyrimidin-4-amine hydrochloride |
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1. Zhang XX, et al. Neural Regen Res. 2016 May;11(5):779-86.
2. Guli X, et al. Neural Plast. 2012;2012:237913.
3. BoSmith RE, et al. Br J Pharmacol. 1993 Sep;110(1):343-9.
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