Thyroid Hormone Receptor (THR) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofThyroid Hormone Receptor (THR) Thyroid Hormone Receptor (THR)

Cat. No.	Product Name	Information
PC-24497	TRβ agonist TG68 TRβ agonist	TRβ agonist TG68 is a potent, selective agonist of thyroid hormone receptor-β (THRβ, TRβ), the prodrug of IS25 (TRβ, EC50=458 nM), promotes lipolysis through the activation of AMPK/ACC pathway.
PC-24487	Eprotirome THRβ agonist	Eprotirome (KB-2115) is a liver-specific thyromimetic and thyroid hormone receptor-beta (TRβ) agonist with modestly higher affinity for TRβ than for TRα, reduces serum cholesterol independent of the LDL receptor.
PC-24184	Simedeutirom THR-β agonist	Simedeutirom is a potent, selective thyroid hormone receptor agonist with EC50 of 0.1-1 uM.
PC-24128	ABX-002 THR-β agonist	Elunetirom (ABX-002, MA-JD21) is a potent, selective, CNS-permeable, thyromimetic thyroid hormone receptor beta (THR-β) agonist.
PC-22746	DCZ5418 TRIP13 inhibitor	DCZ5418 is a specific small molecule inhibitor of thyroid hormone receptor interacting protein 13 (TRIP13), shows anti-multiple myeloma activity in vitro and in vivo.
PC-22745	TRIP13 inhibitor TI17 TRIP13 inhibitor	TI17 is a specific small molecule inhibitor of thyroid hormone receptor interacting protein 13 (Trip13), effectively inhibits the proliferation and induces the cycle arrest and apoptosis of MM cells.

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