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Chemical Structure : AA-861
Catalog No.: PC-62455Not For Human Use, Lab Use Only.
AA-861 (Docebenone) is a potent, selective 5-Lipoxygenase (5-LO) inhibitor with IC50 of 0.8 uM.
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AA-861 (Docebenone) is a potent, selective 5-Lipoxygenase (5-LO) inhibitor with IC50 of 0.8 uM; induces cytotoxic and anti-proliferative effects in 5-LO-positive Capan-2 pancreatic cancer cells; also efficiently inhibits biofilms by preventing the formation of amyloid-like fibers.
Allergy
Discontinued
| M.Wt | 326.436 | |
| Formula | C21H26O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Romero D, et al. Chem Biol. 2013 Jan 24;20(1):102-10.
2. Yoshimoto T, et al. Biochim Biophys Acta. 1982 Nov 12;713(2):470-3.
3. Fischer AS, et al. Br J Pharmacol. 2010 Oct;161(4):936-49.
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