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ALG1001

Chemical Structure : ALG1001

CAS No.: 1307293-62-4

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ALG1001 (Risuteganib；ALG 1001;ALG-1001)

Catalog No.: PC-35165Not For Human Use, Lab Use Only.

ALG1001 (Risuteganib, ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ALG1001 (Risuteganib, ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis; ALG1001 inhibits an integrin-mediated pathway of the vitreoretinal interface, connecting the posterior aspect of the vitreous with the internal limiting membrane of the retina. In blocking this pathway, ALG-1001 helps to achieve vitreous breakdown and separation from the retina.

Other Indication

Phase 2 Clinical

Physicochemical Properties

M.Wt 637.666
Formula C22H39N9O11S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

L-Proline, glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-

References

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