Catalog No.: PC-50004Not For Human Use, Lab Use Only.
AQX 1125 (Rosiptor) is a specific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM.
AQX 1125 (Rosiptor) is a specific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM.
AQX 1125 (Rosiptor) inhibits the pAkt (S473) in MOLT-4 cells, and inhibits cytokine release in mixed splenocytes.
AQX 1125 (Rosiptor) significantly decreases β-hexosaminidase release in mouse BMMCs.
AQX 1125 (Rosiptor) inhibits chemotaxis in human mononuclear cells (EC50=0.26 uM).
AQX 1125 (Rosiptor) suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.
Physicochemical Properties
M.Wt
321.505
Formula
C20H35NO2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Room temperature in continental US; may vary elsewhere
