Chemical Structure : AVE-0991
CAS No.: 304462-19-9
Catalog No.: PC-21225Not For Human Use, Lab Use Only.
AVE 0991 is a potent, selective nonpeptide and orally active angiotensin-(1-7) receptor Mas agonist, displaces the binding of 125I-Ang-(1-7) in Mas-transfected monkey kidney cells (COS) cells with IC50 of 47.5 nM.
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AVE 0991 is a potent, selective nonpeptide and orally active angiotensin-(1-7) receptor Mas agonist, displaces the binding of 125I-Ang-(1-7) in Mas-transfected monkey kidney cells (COS) cells with IC50 of 47.5 nM.
M.Wt | 580.72 | |
Formula | C29H32N4O5S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-[(Ethylamino)carbonyl]-3-[4-[(5-formyl-4-methoxy-2-phenyl-1H-imidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)-2-thiophenesulfonamide |
1. Pinheiro SV, et al. Hypertension. 2004 Oct;44(4):490-6.
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