Chemical Structure : AZ 628
CAS No.: 878739-06-1
Catalog No.: PC-42780Not For Human Use, Lab Use Only.
AZ 628(AZ-628, AZ628) is a potent and selective B-Raf inhibitor with IC50s of 2.14 uM and 0.19 uM for wt Braf and Braf V600E respectively..
Packing | Price | Stock | Quantity |
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10 mg | $88 | In stock | |
25 mg | $176 | In stock | |
50 mg | $288 | In stock | |
100 mg | $448 | In stock | |
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AZ 628(AZ-628, AZ628) is a potent and selective B-Raf inhibitor with IC50s of 2.14 uM and 0.19 uM for wt Braf and Braf V600E respectively.
M.Wt | 451.5197 | |
Formula | C27H25N5O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzamide, 3-(1-cyano-1-methylethyl)-N-[3-[(3,4-dihydro-3-methyl-4-oxo-6-quinazolinyl)amino]-4-methylphenyl]- |
1. McDermott U, et al. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19936-41.
2. Wenglowsky S, et al. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1923-7.
3. Whittaker SR, et al. Cancer Discov. 2013 Mar;3(3):350-62.
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