Chemical Structure : AZD-1092
Catalog No.: PC-61877Not For Human Use, Lab Use Only.
AZD-1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM.
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AZD-1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM; exhibits dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats; shows potential for treatment of type 2 diabetes.
M.Wt | 450.495 | |
Formula | C24H26N4O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Coope GJ, et al. Br J Pharmacol. 2006 Oct;149(3):328-35.
2. Michael J. Waring, et al. Med. Chem. Commun., 2011, 2, 775-779
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