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Chemical Structure : Aurora A-IN-10
CAS No.: 1158838-45-9
Catalog No.: PC-45948Not For Human Use, Lab Use Only.
A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $104 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | $588 | In stock |
Bulk size, bulk discount!
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A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM; displays >1,000-fold selectivity over Aurora B (IC50=3.4 uM) or CDKs; A useful tool compound for investigating the cellular role of Aurora A kinases without the complication of also inhibiting Aurora B.
| M.Wt | 588.075 | |
| Formula | C31H31ClFN7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzamide, N-(2-chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]- |
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1. Aliagas-Martin I, et al. J Med Chem. 2009 May 28;52(10):3300-7.
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