You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-Aurora Kinase-Aurora A-IN-10
Aurora A-IN-10

Chemical Structure : Aurora A-IN-10

CAS No.: 1158838-45-9

Aurora A-IN-10

Catalog No.: PC-45948Not For Human Use, Lab Use Only.

A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM.

Packing Price Stock Quantity
10 mg $104 In stock
50 mg $328 In stock
100 mg $588 In stock

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM; displays >1,000-fold selectivity over Aurora B (IC50=3.4 uM) or CDKs; A useful tool compound for investigating the cellular role of Aurora A kinases without the complication of also inhibiting Aurora B.

Physicochemical Properties

M.Wt 588.075
Formula C31H31ClFN7O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, N-(2-chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-

References

1. Aliagas-Martin I, et al. J Med Chem. 2009 May 28;52(10):3300-7.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: