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Chemical Structure : BAY-1797
CAS No.: 2055602-83-8
Catalog No.: PC-73112Not For Human Use, Lab Use Only.
BAY-1797 (BAY1797) is a potent and selective P2X4 inhibitor/antagonist with IC50 of 211 nM (hP2X4).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $248 | In stock | |
| 25 mg | $428 | In stock | |
| 100 mg | $1080 | In stock | |
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| 1 g | Get quote |
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BAY-1797 (BAY1797) is a potent and selective P2X4 inhibitor/antagonist with IC50 of 211 nM (hP2X4).
BAY-1797 is suitable for in vivo studies in rodents.
BAY-1797 demonstrated anti-inflammatory and anti-nociceptive effects in a mouse complete Freund's adjuvant (CFA) inflammatory pain model.
BAY-1797 displays no or very weak activity on the other P2X ion channels (humanP2X1, P2X23, P2X3, P2X7, all IC50 >8.3 uM), does not inhibit hERG and Carbonic Anhydrase II, also is selective against a panel of off-targets, including GPCRs, ion channels, kinases, and transporters at 10 uM.
| M.Wt | 416.876 | |
| Formula | C20H17ClN2O4S | |
| Appearance | Solid | |
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1. Werner S, et al. J Med Chem. 2019 Dec 26;62(24):11194-11217.
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