BAY876 | GLUT1 inhibitor | Probechem Biochemicals

Chemical Structure : BAY876

CAS No.: 1799753-84-6

BAY876 (BAY-876)

Catalog No.: PC-42031Not For Human Use, Lab Use Only.

BAY-876 (BAY876) is a potent, highly selective and oral bioavailable GLUT1 inhibitor with IC50 of 2 nM.

Packing	Price	Stock
5 mg	$118	In stock
10 mg	$188	In stock
25 mg	$328	In stock
50 mg	$528	In stock
100 mg		Get quote

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Biological Activity

BAY-876 (BAY876) is a potent, highly selective and oral bioavailable GLUT1 inhibitor with IC50 of 2 nM.
BAY-876 displays >100-fold selectivity against GLUT2, GLUT3, and GLUT4.
BAY-876 exhibits good metabolic stability in vitro and high oral bioavailability in vivo.

Physicochemical Properties

M.Wt	496.4164
Formula	C24H16F4N6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 100 mg/mL
Chemical Name/SMILES	2,4-Quinolinedicarboxamide, N4-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-

References

1. Siebeneicher H, et al. ChemMedChem. 2016 Oct 19;11(20):2261-2271.

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BAY876 (BAY-876)

Biological Activity

Physicochemical Properties

References

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