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BMS 830216

Chemical Structure : BMS 830216

CAS No.: 1197420-06-6

BMS 830216 (BMS-830216;BMS830216)

Catalog No.: PC-61122Not For Human Use, Lab Use Only.

The the phosphate ester prodrug of BMS 819881, a potent, selective melanin concentrating hormone receptor 1 (MCHR1) inhibitor with Ki of 10.4 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

The the phosphate ester prodrug of BMS 819881, a potent, selective melanin concentrating hormone receptor 1 (MCHR1) inhibitor with Ki of 10.4 nM; shows potential for treatment of obesity.

Obesity

Phase 2 Discontinued

Physicochemical Properties

M.Wt 548.931
Formula C24H22ClN2O7PS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-(4-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)-2-methoxyphenoxy)-1-cyclopropylethyl dihydrogen phosphate

References

1. Washburn WN, et al. J Med Chem. 2014 Sep 25;57(18):7509-22.

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