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Chemical Structure : BMS 843496
Catalog No.: PC-61346Not For Human Use, Lab Use Only.
A potent and selective PDE10A inhibitor with binding affinity (Kd) of 0.15 nM, IC50 of 2.11 nM.
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A potent and selective PDE10A inhibitor with binding affinity (Kd) of 0.15 nM, IC50 of 2.11 nM; displays a functional selectivity of >100-fold over other PDE subtypes; exhibits antipsychotic-like effects in CAR models.
| M.Wt | 403.889 | |
| Formula | C17H18ClN7OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li YW, et al. Neuropharmacology. 2016 Mar;102:121-35.
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