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CF101

Chemical Structure : CF101

CAS No.: 152918-18-8

CF101 (Piclidenoson, IB-MECA)

Catalog No.: PC-22193Not For Human Use, Lab Use Only.

Piclidenoson (IB-MECA, CF101) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist, shows antiproliferative effect and induces apoptosis in multiple cancer cell types like melanoma, leukemia.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Piclidenoson (IB-MECA, CF101) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist, shows antiproliferative effect and induces apoptosis in multiple cancer cell types like melanoma, leukemia.

Physicochemical Properties

M.Wt 510.29
Formula C18H19IN6O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3S,4R,5R)-3,4-Dihydroxy-5-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide

References

1. Hofer M, et al. Radiat Environ Biophys. 2014 Mar;53(1):211-215.

2. Abedi H, et al. Tumour Biol. 2014 Nov;35(11):11027-11039.

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