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CX-614

Chemical Structure : CX-614

CAS No.: 191744-13-5

CX-614 (CX614)

Catalog No.: PC-61704Not For Human Use, Lab Use Only.

CX-614 is a positive allosteric modulator of AMPA receptors, shows neuroprotective effects for treatment of Parkinson's disease and Alzheimer's disease.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CX-614 is a positive allosteric modulator of AMPA receptors, shows neuroprotective effects for treatment of Parkinson's disease and Alzheimer's disease; has also been shown to reduce the behavioural effects of methamphetamine in mice.

Physicochemical Properties

M.Wt 247.25
Formula C13H13NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one

References

1. Arai AC, et al. Mol Pharmacol. 2000 Oct;58(4):802-13.

2. Dicou E, et al. Brain Res. 2003 Apr 25;970(1-2):221-5.

3. Lauterborn JC, et al. J Pharmacol Exp Ther. 2003 Oct;307(1):297-305.

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