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Cemdomespib

Chemical Structure : Cemdomespib

CAS No.: 1450642-92-8

Cemdomespib (KU-596)

Catalog No.: PC-73397Not For Human Use, Lab Use Only.

Cemdomespib (KU-596) is a novobiocin analogue, C-terminal heat shock protein 90 (Hsp90) modulator that induces Hsp70 levels and manifest neuroprotective activity.

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    Biological Activity

    Cemdomespib (KU-596) is a novobiocin analogue, C-terminal heat shock protein 90 (Hsp90) modulator that induces Hsp70 levels and manifest neuroprotective activity.

    Physicochemical Properties

    M.Wt 447.50
    Formula C24H30FNO6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    References

    1. Zhao H, et al. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3633-7.

    2. Ma J, et al. ACS Chem Neurosci. 2015 Sep 16;6(9):1637-48.

    3. Anyika M, et al. ACS Med Chem Lett. 2015 Dec 9;7(1):67-71.

    4. Zhang X, et al. ACS Chem Neurosci. 2018 Feb 21;9(2):381-390.

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