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Chemical Structure : Compound 14-100
Catalog No.: PC-49415Not For Human Use, Lab Use Only.
Compound 14-100 is a small molecule, orally active inhibitor targeting pancreatic cancer cell chemotaxis in vitro and in vivo, inhibits Hsp70 coding genes.
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Compound 14-100 is a small molecule, orally active inhibitor targeting pancreatic cancer cell chemotaxis in vitro and in vivo, inhibits Hsp70 coding genes.
Compound 14-100 exhibits potent inhibition of Hsp70 coding genes in pancreatic cancer cells.
Compound 14-100 enhances anti-tumor effect of gemcitabine. increases the expression of KRT14 and KRT16 genes.
Compound 14-100 inhibits metastasis of fluorescence-labeled BxPC-3 cells, which were transplanted into the pancreas of nude mice as a subcutaneously grown cancer fragment.
| M.Wt | 331.196 | |
| Formula | C17H12Cl2N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Okamoto S, et al. Biomed Pharmacother. 2022 Nov;155:113733.
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