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Chemical Structure : Cyclo(RGDyK)
CAS No.: 250612-42-1
Catalog No.: PC-70068Not For Human Use, Lab Use Only.
Cyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 25 mg | $398 | In stock | |
| 100 mg | $798 | In stock | |
| 250 mg | Get quote |
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Cyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM; a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including αvβ3.
| M.Wt | 847.72 | |
| Formula | C31H43F6N9O12 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl), bis(trifluoroacetate) (salt) (9CI) |
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1. Haubner R, et al. J Nucl Med. 2001 Feb;42(2):326-36.
2. Chen Y, et al. PLoS One. 2016 Mar 1;11(3):e0149952.
3. Guo L, et al. J Nanosci Nanotechnol. 2014 Jul;14(7):4858-64.
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