Catalog No.: PC-42973Not For Human Use, Lab Use Only.
Cycloheximide (Naramycin A, Actidione) is a widely-used protein synthesis inhibitor that inhibits protein biosynthesis in eukaryotic organisms with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively.
Cycloheximide (Naramycin A, Actidione) is a widely-used protein synthesis inhibitor that inhibits protein biosynthesis in eukaryotic organisms with IC50 of 532.5 nM and 2880 nM for protein synthesis and RNA synthesis in vivo, respectively.
Cycloheximide blocks the elongation phase of eukaryotic translation, binds the ribosome and inhibits eEF2-mediated translocation.
Cycloheximide impairs memory more as footshock intensity increases, enhances memory in an inverted-U dose-response manner at low dose.
Cycloheximide also sensitizes COLO 205 cells to TNF-alpha-induced programmed cell death.
Physicochemical Properties
M.Wt
281.3474
Formula
C15H23NO4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: >33 mg/mL; H2O: 20 mg/mL (Need ultrasonic and warming)
