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Chemical Structure : DC-260126
CAS No.: 346692-04-4
Catalog No.: PC-70042Not For Human Use, Lab Use Only.
DC-260126 is a potent GPR40 agonist with IC50 of 6.28 uM for inhibition of Ca2+ stimulated by linoleic acid.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $328 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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DC-260126 is a potent GPR40 agonist with IC50 of 6.28 uM for inhibition of Ca2+ stimulated by linoleic acid.
DC-260126 reduces GTP-loading and ERK1/2 phosphorylation stimulated by linoleic acid in GPR40-CHO cells.
DC-260126 improves insulin tolerance but not glucose tolerance in obese Zucker rats.
| M.Wt | 307.383 | |
| Formula | C16H18FNO2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(4-butylphenyl)-4-fluorobenzenesulfonamide |
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1. Sun P, et al. PLoS One. 2013 Jun 11;8(6):e66744.
2. Zhang X, et al. Biomed Pharmacother. 2010 Nov;64(9):647-51.
3. Hu H, et al. Biochem Biophys Res Commun. 2009 Dec 18;390(3):557-63.
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