Catalog No.: PC-45372Not For Human Use, Lab Use Only.
Dalbavancin (MDL-63397, BI-397) is a novel second-generation lipoglycopeptide antibiotic with MIC90 values of 0.06 μg/mL and 0.25 μg/mL for Staphylococcus aureus and Bacillus anthracis, respectively.
Dalbavancin (MDL-63397, BI-397) is a novel second-generation lipoglycopeptide antibiotic with MIC90 values of 0.06 μg/mL and 0.25 μg/mL for Staphylococcus aureus and Bacillus anthracis, respectively.
Dalbavancin exerts its bactericidal effect by disrupting cell wall biosynthesis.
Dalbavancin exhibits potent in vitro bactericidal activity against gram-positive pathogens including S. aureus (MRSA), VISA, and non-VanA strains of VRE.
Physicochemical Properties
M.Wt
1816.692
Formula
C88H100Cl2N10O28
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 24 mg/mL
Chemical Name/SMILES
Ristomycin A aglycone, 5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-D-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-α-D-mannopyranosyl-N15-methyl-
References
1. Chen AY, et al. Int J Clin Pract. 2007 May;61(5):853-63.
2. Boucher HW, et al. N Engl J Med. 2014 Jun 5;370(23):2169-79.
