GC-373 | SARS-CoV-2 Mpro inhibitor | Probechem Biochemicals

Chemical Structure : GC-373

Catalog No.: PC-21878Not For Human Use, Lab Use Only.

GC373 is a potent, covalent inhibitor of SARS CoV-2 main protease (MPro) with Kd of 0.15 uM, the reactive aldehyde form of GC376.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GC373 is a potent, covalent inhibitor of SARS CoV-2 main protease (MPro) with Kd of 0.15 uM, the reactive aldehyde form of GC376.

M.Wt	403.48
Formula	C21H29N3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)pentan-2-yl)carbamate

1. Kovalevsky A, et al. J Mol Biol. 2022 Dec 30;434(24):167876.