Chemical Structure : GFH009
CAS No.: 2247481-08-7
Catalog No.: PC-21562Not For Human Use, Lab Use Only.
GFH009 is a potent, highly selective CDK9 inhibitor with IC50 of 9 nM against CDK9/Cyclin T1 complex, blocks RNAP2-mediated transcription maturation.
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M.Wt | 519.11 | |
Formula | C25H35ClN6O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-[[[4-[5-Chloro-2-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino]-4-pyridinyl]-2-thiazolyl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile |
1. Zhou F, et al. Oncotarget. 2023 Dec 20;14:997-1008.
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