GLP1 agonist 1 |CAS:281208-76-2 Probechem Biochemicals

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Chemical Structure : GLP1 agonist 1

GLP1 agonist 1

Catalog No.: PC-70259Not For Human Use, Lab Use Only.

GLP1 agonist 1 is a potent, selective GLP-1 receptor agonist with EC50 of 1.4 uM in cAMP functional assays.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GLP1 agonist 1 is a potent, selective GLP-1 receptor agonist with EC50 of 1.4 uM in cAMP functional assays.
GLP1 agonist 1 does not activate the closely related GLP-2, glucagon, and GIP receptors.
GLP1 agonist 1 potentiates glucose-mediated insulin secretion in the CD1 GLP-1 receptor knockout mice.

Physicochemical Properties

M.Wt	397.215
Formula	C12H5Cl2F3N4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((6,7-dichloro-3-(trifluoromethyl)quinoxalin-2-yl)thio)-5-methyl-1,3,4-thiadiazole

References

1. Knudsen LB, et al. Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):937-42.

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GLP1 agonist 1

Biological Activity

Physicochemical Properties

References

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