GS-5718 | IRAK4 inhibitor | Probechem Biochemicals

Chemical Structure : GS-5718

CAS No.: 2408839-73-4

GS-5718 (Edecesertib, GS5718)

Catalog No.: PC-22269Not For Human Use, Lab Use Only.

GS-5718 (Edecesertib) is a potent, selective, and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor in clinical development for treatment of inflammatory diseases.

Packing	Price	Stock
1 mg	$228	In stock
5 mg	$488	In stock
10 mg	$788	In stock
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Biological Activity

GS-5718 (Edecesertib) is a potent, selective, and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor in clinical development for treatment of inflammatory diseases.

Physicochemical Properties

M.Wt	435.46
Formula	C22H22FN7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[[(1R)-1-Cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-3-pyridinecarboxamide

References

1. Patent WO2020014468 A1.

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GS-5718 (Edecesertib, GS5718)

Biological Activity

Physicochemical Properties

References

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