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Chemical Structure : GSK-2140944
CAS No.: 1075236-89-3
Catalog No.: PC-61938Not For Human Use, Lab Use Only.
GSK-2140944 (Gepotidacin) is a novel potent, selective bacterial type II topoisomerase inhibitor in development for the treatment of conventional and biothreat pathogens, including Gram-positive pathogens and MRSA.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $478 | In stock | |
| 25 mg | $728 | In stock | |
| 100 mg | Get quote | ||
| 200 mg | Get quote | ||
| 1 g | Get quote |
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GSK-2140944 (Gepotidacin) is a novel potent, selective bacterial type II topoisomerase inhibitor in development for the treatment of conventional and biothreat pathogens, including Gram-positive pathogens and MRSA.
GSK-2140944 (Gepotidacin) shows antibacterial activity against MSSA and MRSA isolates (MIC90=0.5 ug/ml).
| M.Wt | 448.527 | |
| Formula | C24H28N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2R)-2-[[4-[[(3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl]amino]-1-piperidinyl]methyl]-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione |
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1. Bax BD, et al. Nature. 2010 Aug 19;466(7309):935-40.
2. Biedenbach DJ, et al. Antimicrob Agents Chemother. 2016 Jan 4;60(3):1918-23.
3. So W, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4956-61.
4. Farrell DJ, et al. Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02047-16.
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