HEC-73543 | Probechem Biochemicals

Chemical Structure : HEC-73543

HEC-73543 (HEC73543;HEC 73543)

Catalog No.: PC-61960Not For Human Use, Lab Use Only.

HEC-73543 is a novel potent, selective, orally bioavailable FLT3 inhibitor for the treatment of refractory acute myeloid leukemia (AML).

Packing	Price	Stock	Quantity

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

HEC-73543 is a novel potent, selective, orally bioavailable FLT3 inhibitor for the treatment of refractory acute myeloid leukemia (AML); shows proliferation inhibition against MV-4-11 and MOLM-13 cells with IC50 of 1.5 and 1.4 nM, respectively; potently inhibits the phosphorylation of FLT3 and its downstream signaling kinases STAT5, AKT and ERK1/2 in tumor tissues, exhibits antitumor activity in an FLT3-ITD subcutaneous tumor xenograft model.

Blood Cancer

Phase 1 Clinical

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

References

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

HEC-73543 (HEC73543;HEC 73543)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.