Chemical Structure : I-2906
CAS No.: 331963-29-2
Catalog No.: PC-45967Not For Human Use, Lab Use Only.
A novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity.
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A novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity; shows good activity against M. tuberculosis H37Ra with MIC of 0.5 ug/ml; significantlt reduces bacterial loads of both lungs and spleen in a murine model.
Bacterial Infection
Preclinical
M.Wt | 443.579 | |
Formula | C25H37N3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-Quinolinecarboxylic acid, 1-ethyl-1,2-dihydro-4-hydroxy-2-oxo-, 2-(1-oxotridecyl)hydrazide |
1. Lu J, et al. Pharmacology. 2010;85(6):365-71.
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