Chemical Structure : JNJ-7706621
CAS No.:
443797-96-4
JNJ-7706621
(JNJ7706621;JNJ 7706621)
Catalog No. : PC-42527Not For Human Use, Lab Use Only.
JNJ-7706621 is a potent, dual CDK/Aurora kinase inhibitor with IC50 of 9/4/11/15 nM for CDK1/CDK2/Aurora A/Aurora B respectively.
Packing Price Stock Quantity 10 mg $188 In stock 0 1 2 3 4 5 25 mg $298 In stock 0 1 2 3 4 5 50 mg $488 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4252701
Biological Activity
JNJ-7706621 is a potent, dual CDK/Aurora kinase inhibitor with IC50 of 9/4/11/15 nM for CDK1/CDK2/Aurora A/Aurora B respectively.
Physicochemical Properties
M.Wt
394.356
Formula
C15H12F2N6O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Benzenesulfonamide, 4-[[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]-
References
1. Emanuel S, et al. Cancer Res.
2. Huang S, et al. Bioorg Med Chem Lett.
3. Seamon JA, et al. Mol Cancer Ther.
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