Ziftomenib (KO-539) | menin-MLL inhibitor

Chemical Structure : KO-539

CAS No.: 2134675-36-6

KO-539 (Ziftomenib, KO 539)

Catalog No.: PC-72438Not For Human Use, Lab Use Only.

KO-539 (Ziftomenib, KO 539) is a potent and selective menin-MLL inhibitor under clinical investigation for treatment of acute myeloid leukemia (AML).

Packing	Price	Stock
5 mg	$358	In stock
10 mg	$548	In stock
25 mg	$858	In stock
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Biological Activity

KO-539 (Ziftomenib, KO 539) is a potent and selective menin-MLL inhibitor under clinical investigation for treatment of acute myeloid leukemia (AML).

Physicochemical Properties

M.Wt	717.875
Formula	C33H42F3N9O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Indole-2-carbonitrile, 4-methyl-5-[[4-[[2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1-[(2S)-2-[4-(methylsulfonyl)-1-piperazinyl]propyl]-

References

1. Cancer Discov. 2021 Feb;11(2):216-217.

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KO-539 (Ziftomenib, KO 539)

Biological Activity

Physicochemical Properties

References

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