Chemical Structure : LY-2119620
CAS No.: 886047-22-9
Catalog No.: PC-60326Not For Human Use, Lab Use Only.
LY 2119620 is a potent, specific,positive allosteric modulator of muscarinic M2 and M4 receptors.
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LY 2119620 is a potent, specific,positive allosteric modulator of muscarinic M2 and M4 receptors.
LY 2119620 displays inimal allosteric agonism for M1, M3, M5 receptors.
LY 2119620 enhances the potency of three muscarinic acetylcholine receptor agonists, ACh, Oxo-M and Iperoxo.
M.Wt | 437.94 | |
Formula | C19H24ClN5O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-Amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy] thieno[2,3-b]pyridine-2-carboxamide |
1. Kruse AC, et al. Nature. 2013 Dec 5;504(7478):101-6.
2. Croy CH, et al. Mol Pharmacol. 2014 Jul;86(1):106-15.
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