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Chemical Structure : LY-2365109 hydrochloride
CAS No.: 1779796-27-8
Catalog No.: PC-42145Not For Human Use, Lab Use Only.
A potent and selective GlyT1 inhibitor with IC50 of 15.8 nM, displays no activity for GlyT2 (IC50>30 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $120 | In stock | |
| 50 mg | $480 | In stock | |
| 100 mg | $840 | In stock |
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A potent and selective GlyT1 inhibitor with IC50 of 15.8 nM, displays no activity for GlyT2 (IC50>30 uM); increases cerebrospinal fluid levels of glycine and potentiates NMDA-induced increases in dialysate levels of neurotransmitters in the prefrontal cortex (PFC) and the striatum.
| M.Wt | 421.9144 | |
| Formula | C22H28ClNO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
Glycine, N-[2-[4-(1,3-benzodioxol-5-yl)-2-(1,1-dimethylethyl)phenoxy]ethyl]-N-methyl-,hydrochloride |
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1. Perry KW, et al. Neuropharmacology. 2008 Oct;55(5):743-54.
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