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Chemical Structure : MB 07811
CAS No.: 852948-13-1
Catalog No.: PC-35609Not For Human Use, Lab Use Only.
MB 07811 (MB07811) is an orally bioavailable, liver-targeted prodrug of MB07344, which is a thyroid hormone receptor-beta agonist (TRβ) agonist, efficiently converted to MB07344 by liver microsomes in vivo.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $198 | In stock | |
| 5 mg | $368 | In stock | |
| 10 mg | $588 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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MB 07811 (MB07811) is an orally bioavailable, liver-targeted prodrug of MB07344, which is a thyroid hormone receptor-beta agonist (TRβ, THR-β) agonist, efficiently converted to MB07344 by liver microsomes in vivo.
MB 07811 reduces cholesterol and both serum and hepatic triglycerides at doses devoid of effects on body weight, glycemia, and the THA.
| M.Wt | 514.98 | |
| Formula | C28H32ClO5P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
trans-(S)-2-[[3,5-Dimethyl-4-(4-hydroxy-3-isopropylbenzyl)phenoxy]methyl]-4-(3-chlorophenyl)-2-oxo-[1,3,2]dioxaphosphorinane |
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1. Erion MD, et al. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15490-5.
2. Ito BR, et al. Br J Pharmacol. 2009 Feb;156(3):454-65.
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