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Chemical Structure : MC-1568
CAS No.: 852475-26-4
Catalog No.: PC-45089Not For Human Use, Lab Use Only.
MC1568 is a potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $98 | In stock | |
| 50 mg | $148 | In stock | |
| 100 mg | Get quote | ||
| 250 mg | Get quote |
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MC1568 is a potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
MC1568 displays 176-fold selectivity over HD1-B.
MC1568 increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20 uM.
MC1568 promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.
| M.Wt | 314.311 | |
| Formula | C17H15FN2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 18.5 mg/mL |
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| Chemical Name/SMILES |
2-Propenamide, 3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-, (2E)- |
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1. Mai A, et al. J Med Chem. 2005 May 5;48(9):3344-53.
2. Duong V, et al. Mol Cancer Res. 2008 Dec;6(12):1908-19.
3. Collins LM, et al. Mol Neurobiol. 2015;51(3):1432-42.
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